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Dr. Reena Agrawal-Rajput

Associate Professor

Contact No.:- +91-79-30514252
Email:- reena.rajput@iar.ac.in

Professional & Educational Qualification

  • Ph.D.: Biotechnology – National Centre for Cell Science, Pune University
  • Post Graduation: M. Sc Biotechnology, GGDU, Bilaspur, CG
  • Graduation: B.Sc. (Microbiology, Botany, Chemistry)
  • Work Experience: 
    • Teaching: 9 years full time, 2 years partially
    • Research: 18 years
    • Prominent Organizations Worked For:
      • National Centre for Cell Science, Pune
      • NIPER, Ahmedabad
      • B. V. Patel PERD Centre, Ahmedabad

Current Research Interest and Area Working On

  1. Macrophage polarization reversal as a strategy to revert tumor microenvironment.
  2. Exploring Chlamydia trachomatis pathogenesis with the aim to establish it as a oncogenic factor for Cervical cancer
  3. Testing macrophage subset depletion as a strategy against Shigella flexneri infection.
  4. In situ cellular reprogramming.

Latest Publications

  1. Patel D, Gaikwad S, Challagundla N, Nivsarkar M, Agrawal-Rajput R. (2018). Spleen tyrosine kinase inhibition ameliorates airway inflammation through modulation of NLRP3 inflammosome and Th17/Treg axis.Int. Immunopharmacol. 2018 Jan; 54: 375-384.
  2. Gaikwad S., Patel D. and Agrawal-Rajput R. (2017). CD40 Negatively Regulates ATP/TLR4 Activated Inflammasome in Microglia. Cellular and Molecular Neurobiology Cell MolNeurobiol. 2017 Mar;37(2):351-359.
  3. Gaikwad S, Naveen C, Agrawal-Rajput R. (2016). Toll-like receptor-4 antagonism mediates benefits during neuroinflammation.Neural Regen Res. 2016 Apr;11(4):552-3.
  4. Naveen CR, Gaikwad S, Agrawal-Rajput R. (2016). Berberine induces neuronal differentiation through inhibition of cancer stemness and epithelial-mesenchymal transition in neuroblastoma cells. Phytomedicine. 2016 Jun 15;23(7):736-44
  5. Gaikwad S, Agrawal-Rajput R. (2015). Lipopolysaccharide from Rhodobactersphaeroides Attenuates Microglia-Mediated Inflammation and Phagocytosis and Directs Regulatory T Cell Response. Int. J. Inflam.2015;doi: 10.1155/2015/361326.)

Awards & Achievements

  1. Best Research Scientist of IAR, Year 2017
  2. Young Investigator award under the Dept. of Biotechnology, India – Rapid Grant for Young Investigator’s (RGYI’s) scheme
  3. Senior Research Fellowship (2004-2006)-Indian Council of Medical Research (ICMR), India
  4. Junior Research Fellowship (2002-2004)-Indian Council of Medical Research (ICMR), India
  5. Gold Medalist for M.Sc. Biotechnology from Guru Ghasi Das University, Bilaspur
  6. Gold Medalist for B.Sc. from Guru Ghasi Das University, Bilaspur

Additional Information

1. Extra Mural Funding

As Project Investigator

  • Unravelling the molecular Mechanism of Berberine against Neuroblastoma Immunosuppressive Tumour Microenvironment. Gujarat State Biotechnology Mission (ongoing)
  • Modulation of TLR5 mediated T regulatory functions in cholera vaccine reactogenicity. Dept. of Biotechnology, India. (completed)
  • Neuroprotective effects of TLR4 antagonist and signaling inhibitors in LPS induced neuronal insults. Dept. of Science and Technology, India. (Completed).
  • Diversifying dectins and inflammasomes in Aspergillusfumigatus specific immune response. Dept. of Biotechnology, India. (Completed).
  • Reprogramming of Immune Cell to Neuron: The new Face of CD40. Gujarat State Biotechnology Mission, Govt. of Gujarat. (Completed).
  • Programme support grant. Dept. of Biotechnology, India. (Completed).

As Co-investigator
The study of mitochondria dynamics during S. aureus infection in human epithelial cells. Indian Council Of Medical Research (ICMR), India. (Completed).

2. Life Membership

  • Indian Immunology Society, India.
  • All India Cell Biology Society, India.

3. Reviewer for Elsevier, Springer, Wiley and other society Publications  
4. External expert to a number of students for their Ph.D., M.Sc. and M.Pharm. Thesis progress as a Research Progress Committee Member
5. Invited as a speaker in a number of conferences

Courses Taught at UG / PG / Ph.D.

  1. Cell Biology (BTCEB 701)
  2. Molecular Cell Biology (CEB 801)
  3. Immunology (IMM 701)
  4. Infection and Immunity (IMM 801)
  5. Recent updates in Immunology research (P 105)
  6. Instrumentation and tools and techniques in Immunology (P 109)
  7. Biology of Diseases (BOD 801)

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